Aging is complex process leading to decrease of adaptation possibilities of the organism, increase of the vulnerability to diseases, decrease of the stamina, cognitive performance, sexual power and overall of the life. Aging-associated disorders caused by accumulation of damage on the cellular level leading to decrease of the functional activity of these cells and cellular death. Under the normal conditions senescent, damaged and dying cells are substituted by the new specialized cells capable to perform specific functions that are generated by adult stem cells. Adult stem cells are located in different tissues of the body. However, the amount and activity of these cells decreases with age. Hence, dynamic balance between the damage and regeneration is shifted to the accumulation of damage events. This leads to the impairment of the activity of the organs.
Damaged cells release pro-inflammatory cytokines. Accumulation of the pro-inflammatory cytokines over the long period of time lead to the development of chronic inflammation that is considered to be important factor of the development of aging-associated disorders. Chronic inflammation in combination with insufficient regeneration lead to the substitution of damaged and dying cells with connective tissue that is not capable to perform specific functions of specialized cells. This results in further decrease in functional activity of the organs. Thus, in order to achieve complex rejuvenation of the organism it is important to restore amount of functionally active stem cells in all tissues of the body and suppress chronic inflammation.
Specialists of the Infinity Clinic have developed elite rejuvenation program «Golden Vial» that is based on administration of combination of all organo-specific types of fetal stem cells, including hematopoietic fetal stem cells, neural fetal stem cells, fetal stem cells of the lungs, heart, liver, fetal stem cells and other types. Fetal stem cells will migrate into corresponding organs to give rise to new specialized cells that will substitute senescent, damaged and dying cells. Also, fetal stem cells will release variety of trophic factors and growth factors that will increase vascularization of impaired tissues, stimulate regeneration and activity of the adult stem cells of the patient. Inti-inflammatory mediators of the fetal stem cells will suppress chronic inflammation.
Effects listed above lead to the improvement of functional activity of the organs, increase of the regenerative potential of the body, decrease of the vulnerability to diseases and risk of development of aging-associated disorders, improvement of the stamina, cognitive performance, sexual power and quality of the life. This is achieved due to rejuvenation from inside (improvement of the tissues and organs of the patient). Additionally, our elite rejuvenation program «Golden Vial» includes special creams for the skin with extracts from fetal stem cells that were produced in our biotechnological laboratory in order to achieve rejuvenation from the outside.
Rejuvenation program «Golden Vial» is only available in Infinity Clinic. Our clinic manages cryobank with large diversity of organ-specific types of fetal stem cells. This provide us with possibility to use combinations of all organ-specific types of fetal stem cells to achieve complex rejuvenation effect on all tissues and organs of the patient. Majority of other stem cells clinics that offer rejuvenation programs usually use only one type of stem cells – adult mesenchymal stem cells. However, under physiological conditions these stem cells differentiate mainly into the cells of bones, cartilage and fat tissues. Thus, for the improvement of all other tissues and organs, administration of corresponding organ-specific types of fetal stem cells is much more efficient.
Efficiency of rejuvenation program «Golden Vial» was evaluated by the positive dynamics of the Frailty Index after administration of fetal stem cells in combination with creams containing fetal stem cell extracts (figures 1,2). The frailty index (FI) is used to measure the health status of older individuals as a proxy measure of aging. It is defined as the proportion of deficits present in an individual out of the total number of age-related health variables studied.
Figure 1. Objective evaluation of the efficiency of elite rejuvenation program «Golden Vial». Graphs illustrating positive dynamics of the values of Frailty Index in different age-groups of women after fetal stem cell treatment.
Figure 2. Objective evaluation of the efficiency of elite rejuvenation program «Golden Vial». Graphs illustrating positive dynamics of the values of Frailty Index in different age-groups of men after fetal stem cell treatment.
